Developing new treatment options for large bone defects and osteoarthritis.
6 academic partners, 3 companies and 3 charitable foundations, working together to train 14 young scientists.
The consortium combines expertise from cell biology, matrix biology and mechanical engineering. Furthermore, involvement of experts in innovative computational modelling will enable us to bring our research to a new level, maximising the use of all the experimental data generated, significantly improving the identification/ prediction of robust therapeutic targets.
Training Early Stage Researchers
CarBon is training 14 high potential scientists to combine knowledge of cartilage & bone developmental biology, pathobiology and tissue engineering with skills in cell culture, animal models, proteomics, biomaterial development, bioreactors and computational modelling.
The balance between cartilage and bone
Identification of cell secreted factors that stimulate or inhibit endochondral ossification. The extracellular matrix and development of novel biomaterial scaffolds. The mechanical environment and use of bioreactors. Towards application and development of new treatments for bone defects and osteoarthritis.
Last April ESR 6 Enrique Andres Sastre went for a week to Frankfurt, hosted by the Dr. Rolf Schwiete Research Unit for Osteoarthritis, Orthopaedic University Hospital Friedrichsheim, Frankfurt, Germany. He worked with Kathrin Maly [...]
Enrique receives the Pauline van Wachum Award at the Dutch Society for Matrix Biology Annual Meeting
On May 17, 2019 CarBon ESR 6 Enrique Andres Sastre received the Pauline van Wachum Award at the Dutch Society for Matrix Biology Annual Meeting. The title of the his presentation was "Thrombospondins -4 and [...]