Project Description

The goal of my research is to study the interaction of inflammation and mechanical loading in endochondral ossification.

As a next step I will evaluate the correlation between selected anti-inflammatory mediators/compounds and mechanically-regulated endochondral ossification response using in-vivo mouse models of hyper- and hypo-loading of joints. My ESR position includes an industrial placement with Eli Lilly and Company in Indianapolis/USA where I will perform a screening for newly-identified anti-inflammatory drugs and their effects on endochondral ossification.